Thermosensitive cross-linked polymer vesicles for controlled release system

被引：56

作者：

Chen, XR ^{[1
]}

Ding, XB ^{[1
]}

Zheng, ZH ^{[1
]}

Peng, YX ^{[1
]}

机构：

[1] Chinese Acad Sci, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China

来源：

NEW JOURNAL OF CHEMISTRY | 2006年 / 30卷 / 04期

关键词：

D O I：

10.1039/b516053g

中图分类号：

O6 [化学];

学科分类号：

0703 [化学];

摘要：

Thermosensitive cross-linked polymer vesicles were formed by self-assembly of block copolymer poly(2-cinnamoylethyl meth acrylate)-block-poly(N-isopropylacrylamide) (PCEMA(61)-b-PNIPAM(22)) and subsequent photo-cross-linking PCEMA shells. The ability of these polymer vesicles to load and release 4-aminopyridine (Apy), a model compound, is discussed. It is found that the polymer vesicles can load a large amount of Apy and release the compound at a tunable rate depending on the temperature. The polymer vesicles also show satisfactory reversible and reproducible thermosensitive release characteristics.

引用

页码：577 / 582

页数：6

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