Labdane diterpenes from the rhizomes of Hedychium coronarium

被引:58
作者
Chimnoi, Nitirat [1 ]
Pisutjaroenpong, Somchai [1 ]
Ngiwsara, Lukana [1 ]
Dechtrirut, Decha [2 ]
Chokchaichamnankit, Daranee [1 ]
Khunnawutmanotham, Nisachon [1 ]
Mahidol, Chulabhorn [1 ]
Techasakul, Supanna [1 ,2 ]
机构
[1] Chulabhorn Res Inst, Bangkok 10210, Thailand
[2] Kasetsart Univ, Fac Sci, Dept Chem, Bangkok 10900, Thailand
关键词
Hedychium coronarium; Zingiberaceae; Labdane diterpenes; Cytotoxicity;
D O I
10.1080/14786410701726434
中图分类号
O69 [应用化学];
学科分类号
081704 [应用化学];
摘要
A new labdane diterpenoid, (E)-labda-8(17),12-dien-15,16-olide (1) together with eight known compounds, coronarin D (2), coronarin D methyl ether (3), coronarin D ethyl ether (4), isocoronarin D (5), coronarin B (6), labda-8(17),11,13-trien-15,16-olide (7), (E)-labda-8(17),12-diene-15,16-dial (8) and 16-hydroxylabda-8(17),11,13-trien-15,16-olide (9), are isolated from the rhizomes of Hedychium coronarium. Compounds 2-4, 5 and 9 are isolated as mixtures of C-15, C-14 and C-16 epimers, respectively. Their structures are determined on the basis of their spectroscopic data. The epimeric mixtures of 2 and 3 have not been reported before. Some of them were evaluated for their cytotoxicity.
引用
收藏
页码:1255 / 1262
页数:8
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