Status and Prospects of Association Mapping in Plants

被引：930

作者：

Zhu, Chengsong ^{[1
]}

Gore, Michael ^{[2
]}

Buckler, Edward S. ^{[3
,4
]}

Yu, Jianming ^{[1
]}

机构：

[1] Kansas State Univ, Dep Agron, Manhattan, KS 66506 USA

[2] Cornell Univ, Dep Plant Breeding & Genet, Ithaca, NY 14853 USA

[3] Cornell Univ, USDA ARS, Ithaca, NY 14853 USA

[4] Cornell Univ, Inst Genom Div, Ithaca, NY 14853 USA

来源：

PLANT GENOME | 2008年 / 1卷 / 01期

基金：

美国国家科学基金会;

关键词：

D O I：

10.3835/plantgenome2008.02.0089

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

There is tremendous interest in using association mapping to identify genes responsible for quantitative variation of complex traits with agricultural and evolutionary importance. Recent advances in genomic technology, impetus to exploit natural diversity, and development of robust statistical analysis methods make association mapping appealing and affordable to plant research programs. Association mapping identifies quantitative trait loci (QTLs) by examining the marker-trait associations that can be attributed to the strength of linkage disequilibrium between markers and functional polymorphisms across a set of diverse germplasm. General understanding of association mapping has increased significantly since its debut in plants. We have seen a more concerted effort in assembling various association-mapping populations and initiating experiments through either candidate-gene or genome-wide approaches in different plant species. In this review, we describe the current status of association mapping in plants and outline opportunities and challenges in complex trait dissection and genomics-assisted crop improvement.

引用

页码：5 / 20

页数：16

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