Discovery and Current Application of Nanozyme

被引:54
作者
Gao Li-Zeng [1 ]
Yan Xi-Yun [1 ]
机构
[1] Chinese Acad Sci, Inst Biophys, Key Lab Prot & Peptide Pharmaceut, Beijing 100101, Peoples R China
关键词
nanozyme; nanomaterial; enzyme mimics; catalysis; tumor detection; wastewater treatment; PEROXIDASE-LIKE ACTIVITY; IRON-OXIDE NANOPARTICLES; INTRINSIC CATALYTIC-ACTIVITY; LINKED-IMMUNOSORBENT-ASSAY; SINGLE-SOURCE PRECURSOR; ENZYME-LIKE ACTIVITIES; MAGNETIC NANOPARTICLES; GLUCOSE DETECTION; HYDROGEN-PEROXIDE; FERROMAGNETIC NANOPARTICLES;
D O I
10.3724/SP.J.1206.2013.00409
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The research on nanozyme which is a novel enzyme mimic based on nanomaterial, is becoming a rapidly emerging field since ferromagnetic nanoparticles with intrinsic peroxidase-like activity was first reported in 2007. Many nanozymes with different morphologies, sizes and components are found to have intrinsic enzyme-like activities and their catalytic mechanisms are systematically investigated. Nanozyme demonstrates high efficient activity, stability and low cost by preparation at large scale. Therefore, nanozymes have promising and multiple applications in many important fields, such as biomedicine, chemical industry, food, agriculture and environment. The discovery of nanozyme not only promotes the basic research in nanotechnology, but also expands the applications of nanomaterials. This review will introduce the latest research progresses in the field of nanozyme.
引用
收藏
页码:892 / 902
页数:11
相关论文
共 64 条
[1]   V2O5 Nanowires with an Intrinsic Peroxidase-Like Activity [J].
Andre, Rute ;
Natalio, Filipe ;
Humanes, Madalena ;
Leppin, Jana ;
Heinze, Katja ;
Wever, Ron ;
Schroeder, H. -C. ;
Mueller, Werner E. G. ;
Tremel, Wolfgang .
ADVANCED FUNCTIONAL MATERIALS, 2011, 21 (03) :501-509
[2]   pH-Tunable Oxidase-Like Activity of Cerium Oxide Nanoparticles Achieving Sensitive Fluorigenic Detection of Cancer Biomarkers at Neutral pH [J].
Asati, Atul ;
Kaittanis, Charalambos ;
Santra, Santimukul ;
Perez, J. Manuel .
ANALYTICAL CHEMISTRY, 2011, 83 (07) :2547-2553
[3]   Oxidase-Like Activity of Polymer-Coated Cerium Oxide Nanoparticles [J].
Asati, Atul ;
Santra, Santimukul ;
Kaittanis, Charalambos ;
Nath, Sudip ;
Perez, J. Manuel .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (13) :2308-2312
[4]   Peroxidase-like activity of water-soluble cupric oxide nanoparticles and its analytical application for detection of hydrogen peroxide and glucose [J].
Chen, Wei ;
Chen, Juan ;
Feng, Ye-Bin ;
Hong, Lei ;
Chen, Qi-Ying ;
Wu, Ling-Feng ;
Lin, Xin-Hua ;
Xia, Xing-Hua .
ANALYST, 2012, 137 (07) :1706-1712
[5]   Dual Enzyme-like Activities of Iron Oxide Nanoparticles and Their Implication for Diminishing Cytotoxicity [J].
Chen, Zhongwen ;
Yin, Jun-Jie ;
Zhou, Yu-Ting ;
Zhang, Yu ;
Song, Lina ;
Song, Mengjie ;
Hu, Sunling ;
Gu, Ning .
ACS NANO, 2012, 6 (05) :4001-4012
[6]   Cerium oxide and platinum nanoparticles protect cells from oxidant-mediated apoptosis [J].
Clark, Andrea ;
Zhu, Aiping ;
Sun, Kai ;
Petty, Howard R. .
JOURNAL OF NANOPARTICLE RESEARCH, 2011, 13 (10) :5547-5555
[7]   Helical Carbon Nanotubes: Intrinsic Peroxidase Catalytic Activity and Its Application for Biocatalysis and Biosensing [J].
Cui, Rongjing ;
Han, Zhida ;
Zhu, Jun-Jie .
CHEMISTRY-A EUROPEAN JOURNAL, 2011, 17 (34) :9377-9384
[8]   Nanostructured FeS as a Mimic Peroxidase for Biocatalysis and Biosensing [J].
Dai, Zhihui ;
Liu, Shaohua ;
Bao, Jianchun ;
Jui, Huangxian .
CHEMISTRY-A EUROPEAN JOURNAL, 2009, 15 (17) :4321-4326
[9]   Nanoparticulate Peroxidase/Catalase Mimetic and Its Application [J].
Deng, Huimin ;
Shen, Wei ;
Peng, Yanfen ;
Chen, Xiaojun ;
Yi, Guangshun ;
Gao, Zhiqiang .
CHEMISTRY-A EUROPEAN JOURNAL, 2012, 18 (29) :8906-8911
[10]   CuS nanoparticles as a mimic peroxidase for colorimetric estimation of human blood glucose level [J].
Dutta, Amit Kumar ;
Das, Sudipto ;
Samanta, Suvendu ;
Samanta, Partha Kumar ;
Adhikary, Bibhutosh ;
Biswas, Papu .
TALANTA, 2013, 107 :361-367