Current directions in co-crystal growth

被引：139

作者：

Blagden, Nicholas ^{[1
,2
]}

Berry, David J. ^{[1
,2
]}

Parkin, Andrew ^{[3
]}

Javed, Hafsa ^{[1
,2
]}

Ibrahim, Asim ^{[1
,2
]}

Gavan, Pauline T. ^{[1
,2
]}

De Matos, Luciana L. ^{[1
,2
]}

Seaton, Colin C. ^{[1
,2
]}

机构：

[1] Univ Bradford, Inst Pharmaceut Innovat, Solid State Pharmaceut Grp, Bradford BD7 1DP, W Yorkshire, England

[2] Univ Bradford, Bradford Sch Pharm, Bradford BD7 1DP, W Yorkshire, England

[3] Univ Glasgow, Dept Chem, WestCHEM, Glasgow G12 8QQ, Lanark, Scotland

来源：

NEW JOURNAL OF CHEMISTRY | 2008年 / 32卷 / 10期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1039/b803866j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this feature article we will focus on the issues relating to the crystal growth of co-crystals, with a particular emphasis on drug development. The initial focus of this perspective is on the relevant literature examples that may be able to inform our understanding with regards co-crystal crystallisation and the allied supramolecular concepts. The second part of this perspective contains selected examples from our own work, which add to the literature perspective. Topics include; nucleation templates, in situ synchrotron XRD studies, solid-state synthesis through mixing and screening strategies.

引用

页码：1659 / 1672

页数：14

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