A printable glucose sensor based on a poly(pyrrole)-latex hybrid material

被引:27
作者
Kros, A
van Hövel, SWFM
Nolte, RJM
Sommerdijk, NAJM
机构
[1] Eindhoven Univ Technol, Lab Macromol & Organ Chem, NL-5600 MB Eindhoven, Netherlands
[2] Univ Nijmegen, Dept Organ Chem, Nijmegen, Netherlands
[3] TNO Nutr & Food Res Inst, Sensor Technol Dept, Eindhoven, Netherlands
关键词
glucose; amperometric biosensor; poly(pyrrole); glucose oxidase; latex spheres;
D O I
10.1016/S0925-4005(01)00909-1
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A printable glucose sensor was obtained by immobilisation of glucose oxidase onto the surface of poly(pyrrole)-coated latex spheres, which were mixed with a conducting ink. The obtained hybrid material was able to amperometrically detect glucose under aerobic as well as anaerobic conditions, without the use of electron mediators. Since all of the steps involved in the preparation of this latex-poly(pyrrole)based ink are performed in solution, in-expensive mass production will be possible. A possible mechanism for this sensor is proposed based on the direct communication between the enzyme and the conducting polymer under anaerobic conditions. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:229 / 233
页数:5
相关论文
共 17 条
[1]   Development of an amperometric sulfite biosensor based on sulfite oxidase with cytochrome c, as electron acceptor, and a screen-printed transducer [J].
Abass, AK ;
Hart, JP ;
Cowell, D .
SENSORS AND ACTUATORS B-CHEMICAL, 2000, 62 (02) :148-153
[2]   Configurations used in the design of screen-printed enzymatic biosensors.: A review [J].
Albareda-Sirvent, M ;
Merkoçi, A ;
Alegret, S .
SENSORS AND ACTUATORS B-CHEMICAL, 2000, 69 (1-2) :153-163
[3]   THE DESIGN OF ENZYME SENSORS BASED ON THE ENZYME STRUCTURE [J].
ALVAREZICAZA, M ;
KALISZ, HM ;
HECHT, HJ ;
AUMANN, KD ;
SCHOMBURG, D ;
SCHMID, RD .
BIOSENSORS & BIOELECTRONICS, 1995, 10 (08) :735-742
[4]   A CONTINUOUS, IMPLANTABLE LACTATE SENSOR [J].
BAKER, DA ;
GOUGH, DA .
ANALYTICAL CHEMISTRY, 1995, 67 (09) :1536-1540
[5]   Covalent attachment of osmium complexes to glucose oxidase and the application of the resulting modified enzyme in an enzyme switch responsive to glucose [J].
Battaglini, F ;
Bartlett, PN ;
Wang, JH .
ANALYTICAL CHEMISTRY, 2000, 72 (03) :502-509
[6]  
CAMMANN K, 1991, ANGEW CHEM, V103, P519
[7]  
Cass A. E. G., 1990, BIOSENSORS PRACTICAL
[8]   CLINICAL USEFULNESS OF THE GLUCOSE-CONCENTRATION IN THE SUBCUTANEOUS TISSUE - PROPERTIES AND PITFALLS OF ELECTROCHEMICAL BIOSENSORS [J].
FISCHER, U ;
REBRIN, K ;
VONWOEDTKE, T ;
ABEL, P .
HORMONE AND METABOLIC RESEARCH, 1994, 26 (11) :515-522
[9]   Glucose biosensor strip in a three electrode configuration based on composite and biocomposite materials applied by planar thick film technology [J].
Galán-Vidal, C ;
Muñoz, J ;
Domínguez, C ;
Alegret, S .
SENSORS AND ACTUATORS B-CHEMICAL, 1998, 52 (03) :257-263
[10]   THE 3D STRUCTURE OF GLUCOSE-OXIDASE FROM ASPERGILLUS-NIGER - IMPLICATIONS FOR THE USE OF GOD AS A BIOSENSOR ENZYME [J].
HECHT, HJ ;
SCHOMBURG, D ;
KALISZ, H ;
SCHMID, RD .
BIOSENSORS & BIOELECTRONICS, 1993, 8 (3-4) :197-203