EGF receptor signalling:: Roles of star and rhomboid revealed

被引：19

作者：

Klämbt, C ^{[1
]}

机构：

[1] Univ Munster, Inst Neurol & Verhaltensbiol, D-48149 Munster, Germany

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 01期

关键词：

D O I：

10.1016/S0960-9822(01)00642-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent studies have clarified how the active form of the Drosophila EGF receptor ligand Spitz is produced: Star chaperones Spitz in the ER and mediates its transport to the Golgi, where the intramembrane serine protease Rhomboid cleaves the Spitz proprotein to initiate secretion.

引用

页码：R21 / R23

页数：3

共 20 条

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