A common enzyme connects Notch signaling and Alzheimer's disease

[1] Notch signaling: Cell fate control and signal integration in development [J]. SCIENCE, 1999, 284 (5415) : 770 - 776

[2] Baumeister R, 1997, Genes Funct, V1, P149

[3] Developmental regulation of presenilin mRNA expression parallels notch expression [J]. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1997, 56 (01) : 40 - 44

[4] A novel proteolytic cleavage involved in Notch signaling:: The role of the disintegrin-metalloprotease TACE [J]. MOLECULAR CELL, 2000, 5 (02) : 207 - 216

[5] Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans [J]. CELL, 2000, 100 (04) : 391 - 398

[6] Evidence that tumor necrosis factor α converting enzyme is involved in regulated α-secretase cleavage of the Alzheimer amyloid protein precursor [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (43) : 27765 - 27767

[7] Presenilin-1 differentially facilitates endoproteolysis of the β-amyloid precursor protein and Notch [J]. NATURE CELL BIOLOGY, 2000, 2 (04) : 205 - 211

[8] De Strooper B, 2000, J CELL SCI, V113, P1857

[9] A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain [J]. NATURE, 1999, 398 (6727) : 518 - 522

[10] Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein [J]. NATURE, 1998, 391 (6665) : 387 - 390

[1] Notch signaling: Cell fate control and signal integration in development [J]. SCIENCE, 1999, 284 (5415) : 770 - 776

[2] Baumeister R, 1997, Genes Funct, V1, P149

[3] Developmental regulation of presenilin mRNA expression parallels notch expression [J]. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1997, 56 (01) : 40 - 44

[4] A novel proteolytic cleavage involved in Notch signaling:: The role of the disintegrin-metalloprotease TACE [J]. MOLECULAR CELL, 2000, 5 (02) : 207 - 216

[5] Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans [J]. CELL, 2000, 100 (04) : 391 - 398

[6] Evidence that tumor necrosis factor α converting enzyme is involved in regulated α-secretase cleavage of the Alzheimer amyloid protein precursor [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (43) : 27765 - 27767

[7] Presenilin-1 differentially facilitates endoproteolysis of the β-amyloid precursor protein and Notch [J]. NATURE CELL BIOLOGY, 2000, 2 (04) : 205 - 211

[8] De Strooper B, 2000, J CELL SCI, V113, P1857

[9] A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain [J]. NATURE, 1999, 398 (6727) : 518 - 522

[10] Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein [J]. NATURE, 1998, 391 (6665) : 387 - 390