Aerobic oxidation of alcohols to carbonyl compounds mediated by poly(ethylene glycol)-supported TEMPO radicals

被引：72

作者：

Benaglia, M

Puglisi, A

Holczknecht, O

Quici, S

Pozzi, G

机构：

[1] CNR, Ist Sci & Tecnol Mol, I-20133 Milan, Italy

[2] Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy

来源：

TETRAHEDRON | 2005年 / 61卷 / 51期

关键词：

alcohols; aldehydes; ketones; oxidation; soluble polymers;

D O I：

10.1016/j.tet.2005.07.107

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two poly(ethylene glycol)-supported TEMPO (PEG-TEMPO) has been successfully applied as soluble, recyclable catalysts in the chemoselective oxidation of primary and benzylic alcohols with molecular oxygen in the presence of Co(NO3)(2) and Mn(NO3)(2) as co-catalysts (Minisci's conditions). Under those conditions, secondary alcohols are also oxidized to ketones, although usually in lower yields. The insertion of a spacer between the PEG moiety and TEMPO has beneficial effects on both the activity and ease of recovery of the supported catalyst. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：12058 / 12064

页数：7

共 58 条

[51] Organocatalytic oxidations mediated by nitroxyl radicals [J].