Simultaneous determination of lipo-alkaloids extracted from Aconitum carmiechaeli using electrospray ionization mass spectrometry and multiple tandem mass spectrometry

被引：27

作者：

Sun, WX ^{[1
]}

Song, FR ^{[1
]}

Cui, M ^{[1
]}

Liu, SY ^{[1
]}

机构：

[1] Acad Sinica, Changchun Inst Appl Chem, 9th Lab, Changchun 130022, Peoples R China

来源：

PLANTA MEDICA | 1999年 / 65卷 / 05期

关键词：

lipo-alkaloids; aconitines; Aconitum carmiechaeli; Ranunculaceae; ESI-MS; MSn;

D O I：

10.1055/s-1999-14086

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Electrospray ionization mass spectrometry (ESI-MS) combined with multiple tandem mass spectrometry (MSn) has been applied for simultaneously determining lipo-alkaloids from the aconite tubers. ESI-MS can give a very good mass separation for lipo-alkaloid mixture and MSn can provide structural information. Accordingly, structures were assigned to 12 known lipo-alkaloids including lipoaconitines, lipomesaconitines, lipodeoxyaconitines, and lipohypaconitines on the base of the information obtained using MSn. Also, four new lipo-alkaloids were found and their structures were interpreted using the MSn data.

引用

页码：432 / 436

页数：5

共 12 条

[1] LONG-CHAIN FATTY-ACID ESTERS OF SOME NORDITERPENOID ALKALOIDS [J].

BAI, YL ;

DESAI, HK ;

PELLETIER, SW .

JOURNAL OF NATURAL PRODUCTS, 1994, 57 (07) :963-970

[2]

Benn M.H., 1983, ALKALOIDS CHEM BIOL, V1, P153

[3]

Fang SP, 1998, RAPID COMMUN MASS SP, V12, P589, DOI 10.1002/(SICI)1097-0231(19980529)12:10<589::AID-RCM200>3.0.CO

[4]

2-Q

[5] Rapid detection and subsequent isolation of bioactive constituents of crude plant extracts [J].

Hostettmann, K ;

Wolfender, JL ;

Rodriguez, S .

PLANTA MEDICA, 1997, 63 (01) :2-10

[6] Determination of Aconitum alkaloids in the tubers of Aconitum japonicum using gas chromatography selected ion monitoring [J].

Ito, K ;

Ohyama, Y ;

Hishinuma, T ;

Mizugaki, M .

PLANTA MEDICA, 1996, 62 (01) :57-59

[7] Method for the simultaneous determination of Aconitum alkaloids and their hydrolysis products by gas chromatography mass spectrometry in human serum [J].

Ito, K ;

Ohyama, Y ;

Konishi, Y ;

Tanaka, S ;

Mizugaki, M .

PLANTA MEDICA, 1997, 63 (01) :75-79

[8]

KITAGAWA I, 1982, CHEM PHARM BULL, V30, P758

[9]

MANSKE RHF, 1979, ALKALOIDS CHEM PHYSL, V18, P4

[10]

Sun WX, 1998, RAPID COMMUN MASS SP, V12, P821, DOI 10.1002/(SICI)1097-0231(19980715)12:13<821::AID-RCM242>3.0.CO

← 1 2 →