Roles of stiffness and excluded volume in DNA denaturation

被引：116

作者：

Carlon, E ^{[1
]}

Orlandini, E

Stella, AL

机构：

[1] Univ Padua, Dipartimento Fis, INFM, I-35131 Padua, Italy

[2] Univ Padua, Sez INFN, I-35131 Padua, Italy

来源：

PHYSICAL REVIEW LETTERS | 2002年 / 88卷 / 19期

关键词：

D O I：

10.1103/PhysRevLett.88.198101

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

The nature and the universal properties of DNA thermal denaturation are investigated by Monte Carlo simulations. For suitable lattice models we determine the exponent c describing the decay of the probability distribution of denaturated loops of length l , Psimilar tol(-c) . If excluded volume effects are fully taken into account, c=2.10(4) is consistent with a first order transition. The stiffness of the double stranded chain has the effect of sharpening the transition, if it is continuous, but not of changing its order and the value of the exponent c, which is also robust with respect to inclusion of specific base-pair sequence heterogeneities.

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页码：4 / 198101

页数：4

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