Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems

被引：346

作者：

Li, Wei ^{[1
]}

Teng, Fei ^{[1
,2
]}

Li, Tianda ^{[1
]}

Zhou, Qi ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Zool, State Key Lab Reprod Biol, Beijing, Peoples R China

[2] Univ Chinese Acad Sci, Beijing, Peoples R China

来源：

NATURE BIOTECHNOLOGY | 2013年 / 31卷 / 08期

基金：

中国国家自然科学基金;

关键词：

KNOCKOUT RATS; EMBRYO MICROINJECTION;

D O I：

10.1038/nbt.2652

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：684 / 686

页数：3

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