The first example of ring-closing olefin metathesis of dehydroamino acids: an application to the synthesis of azabicyclo[XY0]alkanes

被引:30
作者
Manzoni, L
Colombo, M
Scolastico, C
机构
[1] CNR, ISTM, I-20133 Milan, Italy
[2] Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy
[3] Univ Milan, CISI, I-20133 Milan, Italy
关键词
peptidomimetics; ring-closing metathesis (RCM); dehydroamino acids;
D O I
10.1016/j.tetlet.2004.01.126
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The first example of ring-closing metathesis reaction of dehydroamino acids using ruthenium-based catalyst leading to the azabicyclo[X.Y.0]alkanes has been demonstrated. A preliminary investigation into the scope and limitations of the method will be presented. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2623 / 2625
页数:3
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