According to current textbooks, a well-defined three-dimensional structure is a prerequisite for the function of a protein. Is this correct?

被引：16

作者：

Dyson, HJ ^{[1
]}

Wright, PE ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Mol Biol, La Jolla, CA 92037 USA

来源：

IUBMB LIFE | 2006年 / 58卷 / 02期

关键词：

D O I：

10.1080/15216540500484376

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：107 / 109

页数：3

共 36 条

[11] Intrinsic disorder and protein function
Dunker, AK
Brown, CJ
Lawson, JD
Iakoucheva, LM
Obradovic, Z
[J]. BIOCHEMISTRY, 2002, 41 (21) : 6573 - 6582
[12] Unfolded proteins and protein folding studied by NMR
Dyson, HJ
Wright, PE
[J]. CHEMICAL REVIEWS, 2004, 104 (08) : 3607 - 3622
[13] Dyson HJ, 2001, METHOD ENZYMOL, V339, P258
[14] Intrinsically unstructured proteins and their functions
Dyson, HJ
Wright, PE
[J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2005, 6 (03) : 197 - 208
[15] Coupling of folding and binding for unstructured proteins
Dyson, HJ
Wright, PE
[J]. CURRENT OPINION IN STRUCTURAL BIOLOGY, 2002, 12 (01) : 54 - 60
[16] Structural basis for negative regulation of hypoxia-inducible factor-1α by CITED2
Freedman, SJ
Sun, ZYJ
Kung, AL
France, DS
Wagner, G
Eck, MJ
[J]. NATURE STRUCTURAL BIOLOGY, 2003, 10 (07) : 504 - 512
[17] Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1α
Freedman, SJ
Sun, ZYJ
Poy, F
Kung, AL
Livingston, DM
Wagner, G
Eck, MJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (08) : 5367 - 5372
[18] Extended disordered proteins: targeting function with less scaffold
Gunasekaran, K
Tsai, CJ
Kumar, S
Zanuy, D
Nussinov, R
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 2003, 28 (02) : 81 - 85
[19] The importance of intrinsic disorder for protein phosphorylation
Iakoucheva, LM
Radivojac, P
Brown, CJ
O'Connor, TR
Sikes, JG
Obradovic, Z
Dunker, AK
[J]. NUCLEIC ACIDS RESEARCH, 2004, 32 (03) : 1037 - 1049
[20] Intrinsic disorder in cell-signaling and cancer-associated proteins
Iakoucheva, LM
Brown, CJ
Lawson, JD
Obradovic, Z
Dunker, AK
[J]. JOURNAL OF MOLECULAR BIOLOGY, 2002, 323 (03) : 573 - 584

← 1 2 3 4 →