Viral Persistence in HIV Infection: Much Known, Much to Learn

被引：4

作者：

Chun, Tae-Wook ^{[1
]}

Fauci, Anthony S. ^{[1
]}

机构：

[1] NIAID, Immunoregulat Lab, NIH, Bethesda, MD 20892 USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 2013年 / 208卷 / 09期

关键词：

HIV; antiretroviral therapy; viral reservoirs; 2-LTR HIV DNA; intensification; eradication; plasma viremia; ACTIVE ANTIRETROVIRAL THERAPY; RALTEGRAVIR INTENSIFICATION; REPLICATION; RESERVOIR; CURE; GUT; ERADICATION; SUPPRESSION; ACTIVATION; DYNAMICS;

D O I：

10.1093/infdis/jit455

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：1356 / 1358

页数：3

共 26 条

[1]

[Anonymous], 20 C RETR OPP INF AT

[2] Effect of Histone Deacetylase Inhibitors on HIV Production in Latently Infected, Resting CD4+ T Cells From Infected Individuals Receiving Effective Antiretroviral Therapy [J].

Blazkova, Jana ;

Chun, Tae-Wook ;

Belay, Bietel W. ;

Murray, Danielle ;

Justement, J. Shawn ;

Funk, Emily K. ;

Nelson, Amy ;

Hallahan, Claire W. ;

Moir, Susan ;

Wender, Paul A. ;

Fauci, Anthony S. .

JOURNAL OF INFECTIOUS DISEASES, 2012, 206 (05) :765-769

[3] HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects [J].

Buzon, Maria J. ;

Massanella, Marta ;

Llibre, Josep M. ;

Esteve, Anna ;

Dahl, Viktor ;

Puertas, Maria C. ;

Gatell, Josep M. ;

Domingo, Pere ;

Paredes, Roger ;

Sharkey, Mark ;

Palmer, Sarah ;

Stevenson, Mario ;

Clotet, Bonaventura ;

Blanco, Julia ;

Martinez-Picado, Javier .

NATURE MEDICINE, 2010, 16 (04) :460-U143

[4] Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy [J].

Chun, Tae-Wook ;

Nickle, David C. ;

Justement, Jesse S. ;

Meyers, Jennifer H. ;

Roby, Gregg ;

Hallahan, Claire W. ;

Kottilil, Shyam ;

Moir, Susan ;

Mican, Joann M. ;

Mullins, James I. ;

Ward, Douglas J. ;

Kovacs, Joseph A. ;

Mannon, Peter J. ;

Fauci, Anthony S. .

JOURNAL OF INFECTIOUS DISEASES, 2008, 197 (05) :714-720

[5] HIV reservoirs: pathogenesis and obstacles to viral eradication and cure [J].

Chun, Tae-Wook ;

Fauci, Anthony S. .

AIDS, 2012, 26 (10) :1261-1268

[6] HIV-infected individuals receiving effective antiviral therapy for extended periods of time continually replenish their viral reservoir [J].

Chun, TW ;

Nickle, DC ;

Justement, JS ;

Large, D ;

Semerjian, A ;

Curlin, ME ;

O'Shea, MA ;

Hallahan, CW ;

Daucher, M ;

Ward, DJ ;

Moir, S ;

Mullins, JI ;

Kovacs, C ;

Fauci, AS .

JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (11) :3250-3255

[7] Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy [J].

Chun, TW ;

Stuyver, L ;

Mizell, SB ;

Ehler, LA ;

Mican, JAM ;

Baseler, M ;

Lloyd, AL ;

Nowak, MA ;

Fauci, AS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (24) :13193-13197

[8] HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression [J].

Davey, RT ;

Bhat, N ;

Yoder, C ;

Chun, TW ;

Metcalf, JA ;

Dewar, R ;

Natarajan, V ;

Lempicki, RA ;

Adelsberger, JW ;

Millers, KD ;

Kovacs, JA ;

Polis, MA ;

Walker, RE ;

Falloon, L ;

Masur, H ;

Gee, D ;

Baseler, M ;

Dimitrov, DS ;

Fauci, AS ;

Lane, HC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (26) :15109-15114

[9] Towards an HIV cure: a global scientific strategy [J].

Deeks, Steven G. .

NATURE REVIEWS IMMUNOLOGY, 2012, 12 (08) :607-614

[10] HIV Infection, Inflammation, Immunosenescence, and Aging [J].

Deeks, Steven G. .

ANNUAL REVIEW OF MEDICINE, VOL 62, 2011, 2011, 62 :141-155

← 1 2 3 →