Viral Persistence in HIV Infection: Much Known, Much to Learn

被引：4

作者：

Chun, Tae-Wook ^{[1
]}

Fauci, Anthony S. ^{[1
]}

机构：

[1] NIAID, Immunoregulat Lab, NIH, Bethesda, MD 20892 USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 2013年 / 208卷 / 09期

关键词：

HIV; antiretroviral therapy; viral reservoirs; 2-LTR HIV DNA; intensification; eradication; plasma viremia; ACTIVE ANTIRETROVIRAL THERAPY; RALTEGRAVIR INTENSIFICATION; REPLICATION; RESERVOIR; CURE; GUT; ERADICATION; SUPPRESSION; ACTIVATION; DYNAMICS;

D O I：

10.1093/infdis/jit455

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：1356 / 1358

页数：3

共 26 条

[11] Toward an AIDS-Free Generation [J].

Fauci, Anthony S. ;

Folkers, Gregory K. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2012, 308 (04) :343-344

[12] Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy [J].

Finzi, D ;

Hermankova, M ;

Pierson, T ;

Carruth, LM ;

Buck, C ;

Chaisson, RE ;

Quinn, TC ;

Chadwick, K ;

Margolick, J ;

Brookmeyer, R ;

Gallant, J ;

Markowitz, M ;

Ho, DD ;

Richman, DD ;

Siliciano, RF .

SCIENCE, 1997, 278 (5341) :1295-1300

[13] The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial [J].

Gandhi, Rajesh T. ;

Zheng, Lu ;

Bosch, Ronald J. ;

Chan, Ellen S. ;

Margolis, David M. ;

Read, Sarah ;

Kallungal, Beatrice ;

Palmer, Sarah ;

Medvik, Kathy ;

Lederman, Michael M. ;

Alatrakchi, Nadia ;

Jacobson, Jeffrey M. ;

Wiegand, Ann ;

Kearney, Mary ;

Coffin, John M. ;

Mellors, John W. ;

Eron, Joseph J. .

PLOS MEDICINE, 2010, 7 (08)

[14] Increase in 2-Long Terminal Repeat Circles and Decrease in D-dimer After Raltegravir Intensification in Patients With Treated HIV Infection: A Randomized, Placebo-Controlled Trial [J].

Hatano, Hiroyu ;

Strain, Matthew C. ;

Scherzer, Rebecca ;

Bacchetti, Peter ;

Wentworth, Deborah ;

Hoh, Rebecca ;

Martin, Jeffrey N. ;

McCune, Joseph M. ;

Neaton, James D. ;

Tracy, Russell P. ;

Hsue, Priscilla Y. ;

Richman, Douglas D. ;

Deeks, Steven G. .

JOURNAL OF INFECTIOUS DISEASES, 2013, 208 (09) :1436-1442

[15] A Randomized, Controlled Trial of Raltegravir Intensification in Antiretroviral-treated, HIV-infected Patients with a Suboptimal CD4+ T Cell Response [J].

Hatano, Hiroyu ;

Hayes, Timothy L. ;

Dahl, Viktor ;

Sinclair, Elizabeth ;

Lee, Tzong-Hae ;

Hoh, Rebecca ;

Lampiris, Harry ;

Hunt, Peter W. ;

Palmer, Sarah ;

McCune, Joseph M. ;

Martin, Jeffrey N. ;

Busch, Michael P. ;

Shacklett, Barbara L. ;

Deeks, Steven G. .

JOURNAL OF INFECTIOUS DISEASES, 2011, 203 (07) :960-968

[16] Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantaion [J].

Huetter, Gero ;

Nowak, Daniel ;

Mossner, Maximilian ;

Ganepola, Susanne ;

Muessig, Arne ;

Allers, Kristina ;

Schneider, Thomas ;

Hofmann, Joerg ;

Kuecherer, Claudia ;

Blau, Olga ;

Blau, Igor W. ;

Hofmann, Wolf K. ;

Thiel, Eckhard .

NEW ENGLAND JOURNAL OF MEDICINE, 2009, 360 (07) :692-698

[17] Combined approaches for HIV cure [J].

Margolis, David M. ;

Hazuda, Daria J. .

CURRENT OPINION IN HIV AND AIDS, 2013, 8 (03) :230-235

[18] Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study [J].

Saez-Cirion, Asier ;

Bacchus, Charline ;

Hocqueloux, Laurent ;

Avettand-Fenoel, Veronique ;

Girault, Isabelle ;

Lecuroux, Camille ;

Potard, Valerie ;

Versmisse, Pierre ;

Melard, Adeline ;

Prazuck, Thierry ;

Descours, Benjamin ;

Guergnon, Julien ;

Viard, Jean-Paul ;

Boufassa, Faroudy ;

Lambotte, Olivier ;

Goujard, Cecile ;

Meyer, Laurence ;

Costagliola, Dominique ;

Venet, Alain ;

Pancino, Gianfranco ;

Autran, Brigitte ;

Rouzioux, Christine .

PLOS PATHOGENS, 2013, 9 (03)

[19] In vivo evidence for instability of episomal human immunodeficiency virus type 1 cDNA [J].

Sharkey, M ;

Triques, K ;

Kuritzkes, DR ;

Stevenson, M .

JOURNAL OF VIROLOGY, 2005, 79 (08) :5203-5210

[20] Tracking episomal HIV DNA: implications for viral persistence and eradication of HIV [J].

Sharkey, Mark .

CURRENT OPINION IN HIV AND AIDS, 2013, 8 (02) :93-99

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