Vaticanol C, a novel resveratrol tetramer, inhibits cell growth through induction of apoptosis in colon cancer cell lines

被引：52

作者：

Ito, T

Akao, Y ^{[1
]}

Tanaka, T

Iinuma, M

Nozawa, Y

机构：

[1] Gifu Int Inst Biotechnol, Gifu 5050116, Japan

[2] Gifu Pharmaceut Univ, Gifu 5028585, Japan

[3] Gifu Prefectural Inst Hlth & Environm Sci, Kakamigahara 5040838, Japan

来源：

BIOLOGICAL & PHARMACEUTICAL BULLETIN | 2002年 / 25卷 / 01期

关键词：

vaticanol C; apoptosis; human colon cancer cell; cell growth; stilbenoid; Vatica rassak;

D O I：

10.1248/bpb.25.147

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

A novel resveratrol tetramer, vaticanol C, isolated from the stem bark of Vatica rassak markedly suppressed cell growth through induction of apoptosis, which was characterized by nuclear changes and DNA ladder formation, in three different human colon cancer cell lines.

引用

收藏

页码：147 / 148

页数：2

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