In vivo glucose sensing for diabetes management: progress towards non-invasive monitoring

A device for continuous in vivo monitoring of glutose concentration in people with diabetes has been a clinical and research priority for many years but now has an urgency which is probably unquestioned in diabetes tare. The purpose of this article is to explain recent advances in technology that are bringing glutose sensors closer to routine use and to highlight some of the remaining problems. Important new technologies include artificial receptors for glutose, tissue fluid sampling techniques, and new approaches to non-invasive sensing, such as fluorescence lifetime measurements.