Inclusion body myositis: Review of recent literature

被引：18

作者：

Greenberg, Steven A. ^{[1
]}

机构：

[1] Brigham & Womens Hosp, Dept Neurol, Boston, MA 02115 USA

来源：

CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS | 2009年 / 9卷 / 01期

基金：

美国国家卫生研究院;

关键词：

BETA-AMYLOID PRECURSOR; MYXOVIRUS-LIKE STRUCTURES; HUMAN MUSCLE-FIBERS; INFLAMMATORY MYOPATHIES; SKELETAL-MUSCLE; TRANSGENIC MICE; CHRONIC POLYMYOSITIS; MUSCULAR-DYSTROPHY; GENE-EXPRESSION; RIMMED VACUOLES;

D O I：

10.1007/s11910-009-0013-x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Inclusion body myositis (IBM) is a progressive inflammatory skeletal muscle disease of unknown cause and without effective treatment. This article discusses existing literature, emphasizing disease mechanisms and models. In particular, it addresses limitations in the beta-amyloid-mediated theory of IBM myofiber injury, flawed rationales of animal models of this disease, and recent reports regarding treatment.

引用

页码：83 / 89

页数：7

共 70 条

[1] Inclusion body myositis: Clinical and pathological boundaries [J].

Amato, AA ;

Gronseth, GS ;

Jackson, CE ;

Wolfe, GI ;

Katz, JS ;

Bryan, WW ;

Barohn, RJ .

ANNALS OF NEUROLOGY, 1996, 40 (04) :581-586

[2] HUMAN MUSCLE MACROPHAGES EXPRESS BETA-AMYLOID PRECURSOR AND PRION PROTEINS AND THEIR MESSENGER-RNAS [J].

ASKANAS, V ;

SARKOZI, E ;

BILAK, M ;

ALVAREZ, RB ;

ENGEL, WK .

NEUROREPORT, 1995, 6 (07) :1045-1049

[3] Inclusion-body myositis -: A myodegenerative conformational disorder associated with Aβ, protein misfolding, and proteasome inhibition [J].

Askanas, V ;

Engel, WK .

NEUROLOGY, 2006, 66 :S39-S48

[4] BETA-AMYLOID PRECURSOR EPITOPES IN MUSCLE-FIBERS OF INCLUSION-BODY MYOSITIS [J].

ASKANAS, V ;

ALVAREZ, RB ;

ENGEL, WK .

ANNALS OF NEUROLOGY, 1993, 34 (04) :551-560

[5] Inclusion-body myositis, a multifactorial muscle disease associated with aging: current concepts of pathogenesis [J].

Askanas, Valerie ;

Engel, W. King .

CURRENT OPINION IN RHEUMATOLOGY, 2007, 19 (06) :550-559

[6] Epidemiology of inclusion body myositis in the Netherlands:: A nationwide study [J].

Badrising, UA ;

Maat-Schieman, M ;

van Duinen, SG ;

Breedveld, F ;

van Doorn, P ;

van Engelen, B ;

van den Hoogen, F ;

Hoogendijk, J ;

Höweler, C ;

de Jager, A ;

Jennekens, F ;

Koehler, P ;

van der Leeuw, H ;

de Visser, M ;

Verschuuren, JJ ;

Wintzen, AR .

NEUROLOGY, 2000, 55 (09) :1385-1387

[7] Synaptic dysfunction does not contribute to muscle weakness in inclusion-body myositis [J].

Badrising, Umesh A. ;

Verschuuren, Jan J. G. M. ;

Wintzen, Axel R. ;

van Dijk, J. Gert .

MUSCLE & NERVE, 2007, 35 (02) :266-267

[8]

Barkhaus P E, 2007, Electromyogr Clin Neurophysiol, V47, P97

[9] A local antigen-driven humoral response is present in the inflammatory myopathies [J].

Bradshaw, Elizabeth M. ;

Orihuela, Ana ;

McArdel, Shannon L. ;

Salajegheh, Mohammad ;

Amato, Anthony A. ;

Hafler, David A. ;

Greenberg, Steven A. ;

O'Connor, Kevin C. .

JOURNAL OF IMMUNOLOGY, 2007, 178 (01) :547-556

[10]

Capsoni S, 2000, J NEUROSCI RES, V59, P553, DOI 10.1002/(SICI)1097-4547(20000215)59:4<553::AID-JNR11>3.3.CO

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