Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia

被引：21

作者：

Li, Xiang ^{[2
]}

Liu, Zhi ^{[1
]}

Chen, Yun ^{[3
]}

Wang, Li-Juan ^{[2
]}

Zheng, Yi-Nan ^{[2
]}

Sun, Guang-Zhi ^{[1
]}

Ruan, Chang-Chun ^{[1
]}

机构：

[1] Jilin Agr Univ, Inst Agr Modernizat, Changchun 130118, Peoples R China

[2] Jilin Agr Univ, Coll Chinese Med Mat, Changchun 130118, Peoples R China

[3] Wuhan Univ, Res Ctr Med & Struct Biol, Sch Basic Med Sci, Wuhan 430071, Peoples R China

来源：

MOLECULES | 2009年 / 14卷 / 01期

关键词：

Rubia cordifolia; Rubiacordone A; Anthraquinone; Antimicrobial; CONSTITUENTS;

D O I：

10.3390/molecules14010566

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new anthraquinone, Rubiacordone A (1) (6-acetoxy-1-hydroxy-2-methylanthraquinone-3-O-alpha-L-rhamnopyranoside), was isolated together with the known anthraquinone, 1-acetoxy-6-hydroxy-2-methylanthraquinone-3-O-[alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-glucopyranoside] (2), from the dried roots of Rubia cordifolia. Their structures were elucidated on the basis of extensive 1D and 2D-NMR, as well as HRESI-MS spectroscopic analysis. Metabolites 1 and 2 showed considerable antimicrobial activity against Gram-positive bacteria.

引用

页码：566 / 572

页数：7

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