Dendronized iron oxide nanoparticles as contrast agents for MRI

被引:110
作者
Basly, Brice [1 ]
Felder-Flesch, Delphine [1 ]
Perriat, Pascal [2 ]
Billotey, Claire [3 ]
Taleb, Jacqueline [3 ]
Pourroy, Genevieve [1 ]
Begin-Colin, Sylvie [1 ]
机构
[1] UMR CNRS UdS ECPM 7504, IPCMS, F-67034 Strasbourg, France
[2] CNRS INSA Lyon, UMR 5510, Etud Met Phys & Phys Mat Grp, F-69621 Villeurbanne, France
[3] Univ Lyon 1, Lab CREATIS LRMN, CNRS UMR 5220, INSA Lyon,INSERM,U630, F-69621 Villeurbanne, France
关键词
MAGNETITE-BASED NANOPARTICLES; DRUG-DELIVERY; BIOMEDICAL APPLICATIONS; COUPLING AGENT; RESONANCE; THERAPY; FUNCTIONALIZATION; STABILIZATION; DIAGNOSIS; OXIDATION;
D O I
10.1039/b920348f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Covalent attachment, through a phosphonate anchor, of hydrophilic pegylated dendrons on iron oxide nanoparticles results in versatile, robust, and highly relaxing MRI contrast agents.
引用
收藏
页码:985 / 987
页数:3
相关论文
共 41 条
[1]   Versatile PEG-derivatized phosphine oxide ligands for water-dispersible metal oxide nanocrystals [J].
Bin Na, Hyon ;
Lee, In Su ;
Seo, Heonjin ;
Park, Yong Il ;
Lee, Jung Hee ;
Kim, Sang-Wook ;
Hyeon, Taeghwan .
CHEMICAL COMMUNICATIONS, 2007, (48) :5167-5169
[2]   The stabilization and bio-functionalization of iron oxide nanoparticles using heterotelechelic polymers [J].
Boyer, Cyrille ;
Bulmus, Volga ;
Priyanto, Priyanto ;
Teoh, Wey Yang ;
Amal, Rose ;
Davis, Thomas P. .
JOURNAL OF MATERIALS CHEMISTRY, 2009, 19 (01) :111-123
[3]   Ultrasensitive magnetic biosensor for homogeneous immunoassay [J].
Chemla, YR ;
Crossman, HL ;
Poon, Y ;
McDermott, R ;
Stevens, R ;
Alper, MD ;
Clarke, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (26) :14268-14272
[4]   Recent advances in iron oxide nanocrystal technology for medical imaging [J].
Corot, Claire ;
Robert, Philippe ;
Idee, Jean-Marc ;
Port, Marc .
ADVANCED DRUG DELIVERY REVIEWS, 2006, 58 (14) :1471-1504
[5]   Coupling agent effect on magnetic properties of functionalized magnetite-based nanoparticles [J].
Daou, T. J. ;
Greneche, J. M. ;
Pourroy, G. ;
Buathong, S. ;
Derory, A. ;
Ulhaq-Bouillet, C. ;
Donnio, B. ;
Guillon, D. ;
Begin-Colin, S. .
CHEMISTRY OF MATERIALS, 2008, 20 (18) :5869-5875
[6]   Investigation of the grafting rate of organic molecules on the surface of magnetite nanoparticles as a function of the coupling agent [J].
Daou, T. J. ;
Buathong, S. ;
Ung, D. ;
Donnio, B. ;
Pourroy, G. ;
Guillon, D. ;
Begin, S. .
SENSORS AND ACTUATORS B-CHEMICAL, 2007, 126 (01) :159-162
[7]   Phosphate adsorption properties of magnetite-based nanoparticles [J].
Daou, T. J. ;
Begin-Colin, S. ;
Greneche, J. M. ;
Thomas, F. ;
Derory, A. ;
Bernhardt, P. ;
Legare, P. ;
Pourroy, G. .
CHEMISTRY OF MATERIALS, 2007, 19 (18) :4494-4505
[8]   Hydrothermal synthesis of monodisperse magnetite nanoparticles [J].
Daou, T. J. ;
Pourroy, G. ;
Begin-Colin, S. ;
Greneche, J. M. ;
Ulhaq-Bouillet, C. ;
Legare, P. ;
Bernhardt, P. ;
Leuvrey, C. ;
Rogez, G. .
CHEMISTRY OF MATERIALS, 2006, 18 (18) :4399-4404
[9]   Water soluble dendronized iron oxide nanoparticles [J].
Daou, T. J. ;
Pourroy, G. ;
Greneche, J. M. ;
Bertin, A. ;
Felder-Flesch, D. ;
Begin-Colin, S. .
DALTON TRANSACTIONS, 2009, (23) :4442-4449
[10]   Drug delivery and nanoparticles: Applications and hazards [J].
De Jong, Wim H. ;
Borm, Paul J. A. .
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2008, 3 (02) :133-149