DIBAL-H-H2NR and DIBAL-H-HNR1R2•HCl complexes for efficient conversion of lactones and esters to amides

被引：59

作者：

Huang, PQ ^{[1
]}

Zheng, X ^{[1
]}

Deng, XM ^{[1
]}

机构：

[1] Xiamen Univ, Dept Chem, Xiamen 361005, Peoples R China

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 51期

基金：

中国国家自然科学基金;

关键词：

aminolysis; DIBAL H; Weinreb amides; amides;

D O I：

10.1016/S0040-4039(01)01933-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of a lactone or an ester with organoaluminum species generated from DIBAL-H-H2NR or DIBAL-H-(HNRR2)-R-1-HCl complexes provided efficient methods for preparation of amides. Conditions were defined for the preparation of both secondary and tertiary amides, including Weinreb amides in excellent yields, (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：9039 / 9041

页数：3

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