Active surveillance for asymptomatic carriers of carbapenemase-producing Klebsiella pneumoniae in a hospital setting

被引:34
作者
Gagliotti, C. [1 ]
Ciccarese, V. [2 ]
Sarti, M. [2 ]
Giordani, S. [2 ]
Barozzi, A. [2 ]
Braglia, C. [2 ]
Gallerani, C. [2 ]
Gargiulo, R. [2 ]
Lenzotti, G. [2 ]
Manzi, O. [2 ]
Martella, D. [2 ]
Moro, M. L. [1 ]
机构
[1] Agenzia Sanitaria & Sociale Reg Emilia Romagna, I-40127 Bologna, Italy
[2] Nuovo Osped Civile S Agostino Estense, Azienda Unita Sanitaria Locale Modena, Baggiovara, Italy
关键词
Carbapenemase; Carrier; Klebsiella pneumoniae; Screening; ENTEROBACTERIACEAE; INTERVENTION; OUTBREAK; ISRAEL;
D O I
10.1016/j.jhin.2012.11.024
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The spread of carbapenemase-producing Klebsiella pneumoniae (CPKP) is a challenging public health threat. Early identification and isolation of infected patients and carriers are key measures of control. This study describes a CPKP screening strategy in a tertiary Italian hospital. During the five-month study period, 1687 patients were screened by rectal swabs. Of these, 65 (3.9%) tested positive for CPKP; 5.1% of case contacts tested positive. Screening case contacts appears to be the essential surveillance component for detecting asymptomatic carriers of CPKP. The added value of selective CPKP screening on hospital admission depends on the frequency of carriers among incoming patients. (C) 2012 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:330 / 332
页数:3
相关论文
共 11 条
  • [1] Agenzia Sanitaria e Sociale Regionale Emilia-Romagna, 2011, IND PRAT PROT OP DIA
  • [2] [Anonymous], 2010, EURO SURVEILL
  • [3] Carbapenem-Resistant Klebsiella pneumoniae in Post-Acute-Care Facilities in Israel
    Ben-David, Debby
    Masarwa, Samira
    Navon-Venezia, Shiri
    Mishali, Hagit
    Fridental, Ilan
    Rubinovitch, Bina
    Smollan, Gill
    Carmeli, Yehuda
    Schwaber, Mitchell J.
    [J]. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2011, 32 (09) : 845 - 853
  • [4] A Multifaceted Intervention Strategy for Eradication of a Hospital-Wide Outbreak Caused by Carbapenem-Resistant Klebsiella pneumoniae in Southern Israel
    Borer, Abraham
    Eskira, Seada
    Nativ, Ronit
    Saidel-Odes, Lisa
    Riesenberg, Klaris
    Livshiz-Riven, Ilana
    Schlaeffer, Francisc
    Sherf, Michael
    Peled, Nejama
    [J]. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2011, 32 (12) : 1158 - 1165
  • [5] Institutional Control Measures to Curtail the Epidemic Spread of Carbapenem-Resistant Klebsiella pneumoniae: A 4-Year Perspective
    Cohen, Matan J.
    Block, Colin
    Levin, Phillip D.
    Schwartz, Carmela
    Gross, Ilana
    Weiss, Yuval
    Moses, Allon E.
    Benenson, Shmuel
    [J]. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2011, 32 (07) : 673 - 678
  • [6] Comitato di Studio AMCLI per gli Antimicrobici (CoSA), 2012, IND SCREEN COLT PAZ
  • [7] European Centre for Disease Prevention and Control (ECDC), 2011, ANN REP EUR ANT RES
  • [8] Carbapenem-Resistant Enterobacteriaceae: Epidemiology and Prevention
    Gupta, Neil
    Limbago, Brandi M.
    Patel, Jean B.
    Kallen, Alexander J.
    [J]. CLINICAL INFECTIOUS DISEASES, 2011, 53 (01) : 60 - 67
  • [9] Identification and screening of carbapenemase-producing Enterobacteriaceae
    Nordmann, P.
    Gniadkowski, M.
    Giske, C. G.
    Poirel, L.
    Woodford, N.
    Miriagou, V.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2012, 18 (05) : 432 - 438
  • [10] Predictors of Rectal Carriage of Carbapenem-Resistant Enterobacteriaceae (CRE) among Patients with Known CRE Carriage at Their Next Hospital Encounter
    Schechner, Vered
    Kotlovsky, Tali
    Tarabeia, Jalal
    Kazma, Meital
    Schwartz, David
    Navon-Venezia, Shiri
    Carmeli, Yehuda
    [J]. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2011, 32 (05) : 497 - 503