Chemical investigations in the synthesis of O-serinyl aminoribosides

被引：31

作者：

Ginisty, M ^{[1
]}

Gravier-Pelletier, C ^{[1
]}

Le Merrer, Y ^{[1
]}

机构：

[1] Univ Paris 05, UMR 8601, CNRS, Chim & Biochim Pharmacol & Toxicol Lab, F-75270 Paris 06, France

来源：

TETRAHEDRON-ASYMMETRY | 2006年 / 17卷 / 01期

关键词：

D O I：

10.1016/j.tetasy.2005.11.019

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Glycosylation involving D-ribose derivatives and various N-protected tert-butyl L-serinates can be achieved efficiently by careful choice of the activation method at the anomeric position and of the Lewis acid promoter. The conditions described allow the major formation of the P-anomer required for further elaboration to liposidomycin and caprazamycin analogues. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：142 / 150

页数：9

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