Cellular stress and signal transduction responses to human cytomegalovirus infection

被引：30

作者：

Evers, DL

Wang, X

Huang, ES

机构：

[1] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Dept Microbiol & Immunol, Chapel Hill, NC 27599 USA

[3] Univ N Carolina, Dept Med, Chapel Hill, NC 27599 USA

[4] Univ N Carolina, Curriculum Genet & Mol Biol, Chapel Hill, NC 27599 USA

来源：

MICROBES AND INFECTION | 2004年 / 6卷 / 12期

关键词：

cytomegalovirus; signal transduction; cytokine; antiviral;

D O I：

10.1016/j.micinf.2004.05.026

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Human cytomegalovirus (HCMV) receptor-ligand interactions and viral entry excite cellular responses such as receptor tyrosine kinase and mitogen-activated protein kinase signaling, cytoskeletal rearrangement, and the induction of transcription factors, prostaglandins, and cytokines. Bi-phasic stimulation of these pathways, excepting interferon, facilitates productive viral infection and likely contributes to viral pathogenesis. (c) 2004 Elsevier SAS. All rights reserved.

引用

收藏

页码：1084 / 1093

页数：10

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