Efficient RhII binaphthol phosphate catalysts for enantioselective intramolecular tandem carbonyl ylide formation-cycloaddition of α-diazo-β-keto esters

被引：79

作者：

Hodgson, DM

Stupple, PA

Johnstone, C

机构：

[1] Univ Oxford, Dept Chem, Dyson Perrins Lab, Oxford OX1 3QY, England

[2] AstraZeneca, Macclesfield SK10 4TG, Cheshire, England

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 21期

关键词：

D O I：

10.1039/a906787f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Catalytic enantioselective tandem carbonyl ylide formation-cycloadditions of alpha-diazo-beta-keto ester 1 using 0.5 mol% dirhodium tetrakis(1,1'-binaphthyl-2,2'-diyl phosphate) catalysts 7-9 and 14 to give the cycloadduct 3 in good yields and up to 90% ee are described.

引用

页码：2185 / 2186

页数：2

共 15 条

[11] ASYMMETRIC DIPOLAR CYCLOADDITION REACTIONS OF DIAZO-COMPOUNDS MEDIATED BY A BINAPHTHOLPHOSPHATE RHODIUM CATALYST [J].