NK T cells are a source of early interleukin-4 following infection with third-stage larvae of the Filarial nematode Brugia pahangi

被引:19
作者
Balmer, P [1 ]
Devaney, E [1 ]
机构
[1] Univ Glasgow, Dept Vet Parasitol, Glasgow G61 1QH, Lanark, Scotland
关键词
D O I
10.1128/IAI.70.4.2215-2219.2002
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Infection of C57BL/6 mice with the third-stage larvae of Brugia pahangi results in a rapid expansion of NK1.1(+) T cells in the spleen and draining lymph nodes. NK T cells produced interleukin-4 in the spleen within 24 h of infection, and these cells were CD4(-).
引用
收藏
页码:2215 / 2219
页数:5
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