Two-photon probes for biomedical applications

被引:31
作者
Lim, Chang Su [1 ]
Cho, Bong Rae [1 ]
机构
[1] Korea Univ, Dept Chem, Seoul 136701, South Korea
基金
新加坡国家研究基金会;
关键词
Autophagy; Lipid rafts; Two-photon probes; TURN-ON PROBE; FLUORESCENT-PROBE; LIPID RAFTS; HYDROGEN-PEROXIDE; ACIDIC VESICLES; LIVE CELLS; AUTOPHAGY; MITOCHONDRIA; SEGREGATION; DIAGNOSIS;
D O I
10.5483/BMBRep.2013.46.4.045
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two-photon microscopy (TPM), which uses two photons of lower energy as the excitation source, is a vital tool in biology and clinical science, due to its capacity to image deep inside intact tissues for a long period of time. To make TPM a more versatile tool in biomedical research, we have developed a variety of two-photon probes for specific applications. In this mini review, we will briefly discuss two-photon probes for lipid rafts, lysosomes, mitochondria, and pH, and their biomedical applications.
引用
收藏
页码:188 / 194
页数:7
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