A two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue

被引:143
作者
Chung, Chul [3 ]
Srikun, Duangkhae [1 ,2 ]
Lim, Chang Su [3 ]
Chang, Christopher J. [1 ,2 ]
Cho, Bong Rae [3 ]
机构
[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Howard Hughes Med Inst, Berkeley, CA 94720 USA
[3] Korea Univ, Dept Chem, Seoul 136701, South Korea
关键词
BIOLOGY; PHOSPHORYLATION; H2O2;
D O I
10.1039/c1cc13583j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report a two-photon fluorescent probe (PN1) that can be excited by 750 nm femto-second pulses, shows high photostability and negligible toxicity, and can visualize H2O2 distribution in live cells and tissue by two-photon microscopy.
引用
收藏
页码:9618 / 9620
页数:3
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