Hyperbranched polymers for controlled release of cisplatin

被引：52

作者：

Haxton, Katherine J. ^{[1
,2
]}

Burt, Helen M. ^{[1
]}

机构：

[1] Univ British Columbia, Fac Pharmaceut Sci, Vancouver, BC V6T 1Z3, Canada

[2] Univ Keele, Sch Phys & Geog Sci, Keele ST5 5BG, Staffs, England

来源：

DALTON TRANSACTIONS | 2008年 / 43期

基金：

加拿大自然科学与工程研究理事会; 加拿大健康研究院;

关键词：

D O I：

10.1039/b809949a

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Hyperbranched polymers based on a polyether and polyester have been modified and used as macromolecular ligands for the anticancer drug cisplatin, giving controlled release of the drug over 7 days.

引用

页码：5872 / 5875

页数：4

共 16 条

[1] Functional polymers in drug delivery: carrier-supported CDDP (cis-platin) complexes of polycarboxylates - effect on human ovarian carcinoma [J].

Avichezer, D ;

Schechter, B ;

Arnon, R .

REACTIVE & FUNCTIONAL POLYMERS, 1998, 36 (01) :59-69

[2] Three generations of α,γ-diaminobutyric acid modified poly(propyleneimine) dendrimers and their cisplatin-type platinum complexes [J].

Bellis, E. ;

Hajba, L. ;

Kovacs, B. ;

Sandor, K. ;

Kollar, L. ;

Kokotos, G. .

JOURNAL OF BIOCHEMICAL AND BIOPHYSICAL METHODS, 2006, 69 (1-2) :151-161

[3] A flexible approach to the preparation of polymer scaffolds for tissue engineering [J].

Borgaonkar, Poonam ;

Sharma, Sachin ;

Chen, Ming ;

Bhowmick, Sankha ;

Schmidt, Daniel F. .

MACROMOLECULAR BIOSCIENCE, 2007, 7 (02) :201-207

[4] Searching for the Magic Bullet: Anticancer Platinum Drugs Which Can Be Accumulated or Activated in the Tumor Tissue [J].

Galanski, Markus ;

Keppler, Bernhard K. .

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2007, 7 (01) :55-73

[5] SPECTROPHOTOMETRIC DETERMINATION OF PLATINUM WITH ORTHO-PHENYLENEDIAMINE [J].

GOLLA, ED ;

AYRES, GH .

TALANTA, 1973, 20 (02) :199-210

[6] Polymer therapeutics: Concepts and applications [J].

Haag, R ;

Kratz, F .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (08) :1198-1215

[7] Biocompatibility testing of branched and linear polyglycidol [J].

Kainthan, RK ;

Janzen, J ;

Levin, E ;

Devine, DV ;

Brooks, DE .

BIOMACROMOLECULES, 2006, 7 (03) :703-709

[8] The resurgence of platinum-based cancer chemotherapy [J].

Kelland, Lloyd .

NATURE REVIEWS CANCER, 2007, 7 (08) :573-584

[9] Dendrimer-platinate: a novel approach to cancer chemotherapy [J].

Malik, N ;

Evagorou, EG ;

Duncan, R .

ANTI-CANCER DRUGS, 1999, 10 (08) :767-776

[10]

*PERST AB, SE28480 PERST AB

← 1 2 →