Co-evolution of a primordial peptide-presentation system and cellular immunity

被引：27

作者：

Boehm, T ^{[1
]}

机构：

[1] Max Planck Inst Immunobiol, Dept Dev Immunol, D-79108 Freiburg, Germany

来源：

NATURE REVIEWS IMMUNOLOGY | 2006年 / 6卷 / 01期

关键词：

D O I：

10.1038/nri1749

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

How did early vertebrates survive when their lymphocytes began to use antigen receptors with random specificities, despite their potential for extensive self-reactivity? Here, I propose that the quality-control mechanisms that tame self-reactivity in the adaptive immune system were derived, at least in part, from an ancient mechanism that guided sexual selection on the basis of evaluating genetic relatedness.

引用

页码：79 / 84

页数：6

共 54 条

[31] Mate choice decisions of stickleback females predictably modified by MHC peptide ligands [J].

Milinski, M ;

Griffiths, S ;

Wegner, KM ;

Reusch, TBH ;

Haas-Assenbaum, A ;

Boehm, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (12) :4414-4418

[32] Genes and ligands for odorant, vomeronasal and taste receptors [J].

Mombaerts, P .

NATURE REVIEWS NEUROSCIENCE, 2004, 5 (04) :263-278

[33] Removal of the block to self fertilizatioai in the ascidian ciona [J].

Morgan, TH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1923, 9 :170-171

[34] Potential immunocompetence of proteolytic fragments produced by proteasomes before evolution of the vertebrate immune system [J].

Niedermann, G ;

Grimm, R ;

Geier, E ;

Maurer, M ;

Realini, C ;

Gartmann, C ;

Soll, J ;

Omura, S ;

Rechsteiner, MC ;

Baumeister, W ;

Eichmann, K .

JOURNAL OF EXPERIMENTAL MEDICINE, 1997, 186 (02) :209-220

[35] Structure of a pheromone receptor-associated MHC molecule with an open and empty groove [J].

Olson, R ;

Huey-Tubman, KE ;

Dulac, C ;

Bjorkman, PJ .

PLOS BIOLOGY, 2005, 3 (08) :1436-1448

[36] Variable lymphocyte receptors in hagfish [J].

Pancer, Z ;

Saha, NR ;

Kasamatsu, J ;

Suzuki, T ;

Amemiya, CT ;

Kasahara, M ;

Cooper, MD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (26) :9224-9229

[37] Somatic diversification of variable lymphocyte receptors in the agnathan sea lamprey [J].

Pancer, Z ;

Amemiya, CT ;

Ehrhardt, GRA ;

Ceitlin, J ;

Gartland, GL ;

Cooper, MD .

NATURE, 2004, 430 (6996) :174-180

[38] How do major histocompatibility complex genes influence odor and mating preferences? [J].

Penn, D ;

Potts, W .

ADVANCES IN IMMUNOLOGY, VOL 69, 1998, 69 :411-436

[39] EVOLUTION OF DIVERSITY AT THE MAJOR HISTOCOMPATIBILITY COMPLEX [J].

POTTS, WK ;

WAKELAND, EK .

TRENDS IN ECOLOGY & EVOLUTION, 1990, 5 (06) :181-187

[40] The spawning pheromone cysteine-glutathione disulfide ('nereithione') arouses a multicomponent nuptial behavior and electrophysiological activity in Nereis succinea males [J].

Ram, JL ;

Müller, CT ;

Beckmann, M ;

Hardege, JD .

FASEB JOURNAL, 1999, 13 (08) :945-952

← 1 2 3 4 5 6 →