Oblongifolins A-D, polyprenylated benzoylphloroglucinol derivatives from Garcinia oblongifolia

被引：76

作者：

Hamed, Wafaa

Brajeul, Solenn

Mahuteau-Betzer, Florence

Thoison, Odile

Mons, Stephane

Delpech, Bernard

Van Hung, Nguyen

Sevenet, Thierry

Marazano, Christian

机构：

[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

[2] NCST, Inst Chem, Hanoi, Vietnam

来源：

JOURNAL OF NATURAL PRODUCTS | 2006年 / 69卷 / 05期

关键词：

D O I：

10.1021/np050543s

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Oblongifolins A-D ( 2-5), four new polyprenylated 3,4-dihydroxybenzoylphloroglucinol compounds, were isolated from the bark of Garcinia oblongifolia collected in Vietnam. The bark was also found to contain the known compounds camboginol and guttiferone B. Extraction of the leaves gave 2 and camboginol. Details of the structure elucidation of 2-5 and stereochemical comparisons with known natural derivatives of general formula 1a, b are presented. The biological activity of these compounds concerning interactions with tubulin was investigated.

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页码：774 / 777

页数：4

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