Preparation and use of (S)-O-acetyllactyl chloride (Mosandl's reagent) as a chiral derivatizing agent

被引：9

作者：

Buisson, D ^{[1
]}

Azerad, R ^{[1
]}

机构：

[1] Univ Paris 05, Chim & Biochim Pharmacol & Toxicol Lab, UMR 8601, F-75270 Paris 06, France

来源：

TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 15期

关键词：

D O I：

10.1016/S0957-4166(99)00285-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(S)-O-Acetyllactyl chloride is used as a versatile chiral derivatizing agent for the chromatographic determination of the enantiomeric excesses of alcohols or amines. However, some precautions must be taken to avoid its racemization during preparation and use. In addition, the racemic counterpart of this reagent can be used to determine the best analytical separation conditions. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2997 / 3002

页数：6

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