Expedient total syntheses of WIN 64745 and WIN 64821

被引：70

作者：

Perez-Balado, Carlos ^{[1
]}

de Lera, Angel R. ^{[1
]}

机构：

[1] Univ Vigo, Fac Quim, Dept Quim Organ, Vigo 36310, Spain

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 17期

关键词：

D O I：

10.1021/ol8013073

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bispyrrolidinoindoline diketopiperazine alkaloids were synthesized from a common intermediate in seven steps from commercially available amino acids. This versatile synthetic strategy has led to the accomplishment of the first total synthesis of heterodimeric WIN 64745 and a novel approach to homodimeric WIN 64821.

引用

页码：3701 / 3704

页数：4

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