A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis

被引：102

作者：

Spears, KJ ^{[1
]}

Roe, AJ ^{[1
]}

Gally, DL ^{[1
]}

机构：

[1] Univ Edinburgh, Ctr Infect Dis, Zooton & Anim Pathogens Res Lab, Edinburgh EH16 4SB, Midlothian, Scotland

来源：

FEMS MICROBIOLOGY LETTERS | 2006年 / 255卷 / 02期

基金：

英国生物技术与生命科学研究理事会;

关键词：

enteropathogenic Escherichia coli; enterohaemorrhagic Escherichia coli; Shiga toxin; type III secretion;

D O I：

10.1111/j.1574-6968.2006.00119.x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This review covers enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) infections, focusing on differences in their virulence factors and regulation. While Shiga-toxin expression from integrated bacteriophages sets EHEC apart from EPEC, EHEC infections often originate from asymptomatic carriage in ruminants whereas human EPEC are considered to be overt pathogens and more host-restricted. In part, these differences reflect variation in adhesin repertoire, type III-secreted effectors and the way in which these factors are regulated.

引用

页码：187 / 202

页数：16

共 126 条

[71] The Per regulon of enteropathogenic Escherichia coli:: identification of a regulatory cascade and a novel transcriptional activator, the locus of enterocyte effacement (LEE)-encoded regulator (Ler)
Mellies, JL
Elliott, SJ
Sperandio, V
Donnenberg, MS
Kaper, JB
[J]. MOLECULAR MICROBIOLOGY, 1999, 33 (02) : 296 - 306
[72] Shiga toxin 1 from Escherichia coli blocks activation and proliferation of bovine lymphocyte subpopulations in vitro
Menge, C
Wieler, LH
Schlapp, T
Baljer, G
[J]. INFECTION AND IMMUNITY, 1999, 67 (05) : 2209 - 2217
[73] Phenotypic and functional characterization of intraepithelial lymphocytes in a bovine ligated intestinal loop model of enterohaemorrhagic Escherichia coli infection
Menge, C
Stamm, I
van Diemen, PM
Sopp, P
Baljer, G
Wallis, TS
Stevens, MP
[J]. JOURNAL OF MEDICAL MICROBIOLOGY, 2004, 53 (06) : 573 - 579
[74] Nakao H, 2000, J NAT TOXINS, V9, P299
[75] Attaching and effacing Escherichia coli isolated from dogs in Brazil:: characteristics and serotypic relationship to human enteropathogenic E-coli (EPEC)
Nakazato, G
Gyles, C
Ziebell, K
Keller, R
Trabulsi, LR
Gomes, TAT
Irino, K
Da Silveira, WD
De Castro, AFP
[J]. VETERINARY MICROBIOLOGY, 2004, 101 (04) : 269 - 277
[76] Nataro JP, 1998, CLIN MICROBIOL REV, V11, P403
[77] The serine protease motif of EspC from enteropathogenic Escherichia coli produces epithelial damage by a mechanism different from that of pet toxin from enteroaggregative E-coli
Navarro-García, F
Canizalez-Roman, A
Sui, BQ
Nataro, JP
Azamar, Y
[J]. INFECTION AND IMMUNITY, 2004, 72 (06) : 3609 - 3621
[78] Enterohaemorrhagic E. coli in veterinary medicine
Naylor, SW
Gally, DL
Low, JC
[J]. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2005, 295 (6-7) : 419 - 441
[79] Escherichia coli O157: H7 forms attaching and effacing lesions at the terminal rectum of cattle and colonization requires the LEE4 operon
Naylor, SW
Roe, AJ
Nart, P
Spears, K
Smith, DGE
Low, JC
Gally, DL
[J]. MICROBIOLOGY-SGM, 2005, 151 : 2773 - 2781
[80] Lymphoid follicle-dense mucosa at the terminal rectum is the principal site of colonization of enterohemorrhagic Escherichia coli O157:H7 in the bovine host
Naylor, SW
Low, JC
Besser, TE
Mahajan, A
Gunn, GJ
Pearce, MC
McKendrick, IJ
Smith, DGE
Gally, DL
[J]. INFECTION AND IMMUNITY, 2003, 71 (03) : 1505 - 1512

← 3 4 5 6 7 8 9 10 11 12 →