2(S)-((3,5-bis(trifluoromethyl)benzyl)oxy)-3(S)-phenyl-4-((3-oxo-1,2,4-triazol-5-yl)methyl)morpholine .1. A potent, orally active, morpholine-based human neurokinin-1 receptor antagonist

被引：71

作者：

Hale, JJ

Mills, SG

MacCoss, M

Shah, SK

Qi, HB

Mathre, DJ

Cascieri, MA

Sadowski, S

Strader, CD

MacIntyre, DE

Metzger, JM

机构：

[1] Merck Research Laboratories, Rahway

[2] Schering Plough Research Institute, Kenilworth, NJ 07033

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1996年 / 39卷 / 09期

关键词：

NONPEPTIDE ANTAGONIST; INFLAMMATION; BINDING;

D O I：

10.1021/jm950654w

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：1760 / 1762

页数：3

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