The Collaborative Cross, developing a resource for mammalian systems genetics: A status report of the Wellcome Trust cohort

被引：99

作者：

Iraqi, Fuad A. ^{[1
]}

Churchill, Gary ^{[2
]}

Mott, Richard ^{[3
]}

机构：

[1] Tel Aviv Univ, Dept Human Microbiol, Sackler Fac Med, IL-69978 Tel Aviv, Israel

[2] Jackson Lab, Bar Harbor, ME 04609 USA

[3] Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England

来源：

MAMMALIAN GENOME | 2008年 / 19卷 / 06期

基金：

英国惠康基金;

关键词：

D O I：

10.1007/s00335-008-9113-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We report on the progress of a project funded by the Wellcome Trust to produce over 100 recombinant inbred mouse lines as part of the Collaborative Cross (CC) genetic reference panel. These new strains of mice are being derived from a set of eight genetically diverse founders. The genomes of the finished strains will be mosaics of the founder strains' genomes with a high density of independent recombination breakpoints. The CC mice will be available for distribution free of any intellectual property constraints to serve as a community resource for systems genetics studies.

引用

页码：379 / 381

页数：3

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