Genetical genomics: the added value from segregation

被引：672

作者：

Jansen, RC ^{[1
]}

Nap, JP ^{[1
]}

机构：

[1] Plant Res Int BV, NL-6700 AA Wageningen, Netherlands

来源：

TRENDS IN GENETICS | 2001年 / 17卷 / 07期

关键词：

D O I：

10.1016/S0168-9525(01)02310-1

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The recent successes of genome-wide expression profiling in biology tend to overlook the power of genetics. We here propose a merger of genomics and genetics into 'genetical genomics'. This involves expression profiling and marker-based fingerprinting of each individual of a segregating population, and exploits all the statistical tools used in the analysis of quantitative trait loci. Genetical genomics will combine the power of two different worlds in a way that is likely to become instrumental in the further unravelling of metabolic, regulatory and developmental pathways.

引用

页码：388 / 391

页数：4

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