Host-retrovirus arms race: Trimming the budget

被引：13

作者：

Jern, Patric ^{[1
]}

Coffin, John M. ^{[1
]}

机构：

[1] Tufts Univ, Sch Med, Dept Mol Biol & Microbiol, Boston, MA 02111 USA

来源：

CELL HOST & MICROBE | 2008年 / 4卷 / 03期

关键词：

D O I：

10.1016/j.chom.2008.08.008

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In this issue of Cell Host & Microbe, OhAinle et al., 2008 report that APOBEC3H, a potent innate retroviral restriction factor in primates, lost its function twice independently during recent evolution in humans, stressing an ever present trade-off between benefit and cost of protection against pathogens.

引用

页码：196 / 197

页数：2

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