Hemolytic Uremic Syndrome in a 65-Year-Old Male Linked to a Very Unusual Type of stx2e- and eae-Harboring O51:H49 Shiga Toxin-Producing Escherichia coli

被引：40

作者：

Fasel, Dominique ^{[1
]}

Mellmann, Alexander ^{[2
,3
]}

Cernela, Nicole ^{[4
]}

Haechler, Herbert ^{[4
]}

Fruth, Angelika ^{[5
]}

Khanna, Nina ^{[1
]}

Egli, Adrian ^{[6
]}

Beckmann, Christiane ^{[7
]}

Hirsch, Hans H. ^{[1
,7
,8
]}

Goldenberger, Daniel ^{[6
]}

Stephan, Roger ^{[4
]}

机构：

[1] Univ Basel Hosp, Div Infect Dis & Hosp Epidemiol, CH-4031 Basel, Switzerland

[2] Univ Munster, Inst Hyg, D-48149 Munster, Germany

[3] Univ Munster, Natl Consulting Lab Hemolyt Urem Syndrome, D-48149 Munster, Germany

[4] Univ Zurich, Inst Food Safety & Hyg, Natl Ctr Enteropathogen Bacteria & Listeria, Zurich, Switzerland

[5] Robert Koch Inst, Wernigerode, Germany

[6] Univ Basel Hosp, Div Clin Microbiol, CH-4031 Basel, Switzerland

[7] Univ Basel, Dept Biomed, Basel, Switzerland

[8] Univ Basel, Dept Biomed, Div Infect Diagnost, Basel, Switzerland

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2014年 / 52卷 / 04期

关键词：

STRAINS; INFECTIONS; DIARRHEA; GERMANY; VARIANTS; SUBTYPES; CHILDREN;

D O I：

10.1128/JCM.03459-13

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We report on a 65-year-old male patient with a Shiga toxin-producing Escherichia coli O51:H49 gastrointestinal infection and sepsis associated with hemolytic uremic syndrome (HUS) with a fatal outcome. The strains isolated harbored stx(2e) and eae, a very unusual and new virulence profile for an HUS-associated enterohemorrhagic E. coli.

引用

页码：1301 / 1303

页数：3

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