Cortical excitability and recovery curve analysis in generalized epilepsy

被引：46

作者：

Brodtmann, A ^{[1
]}

Macdonell, RAL ^{[1
]}

Gilligan, AK ^{[1
]}

Curatolo, J ^{[1
]}

Berkovic, SF ^{[1
]}

机构：

[1] Austin Repatriat Med Ctr, Dept Neurol, Heidelberg, Vic, Australia

来源：

NEUROLOGY | 1999年 / 53卷 / 06期

关键词：

idiopathic generalized epilepsy; cortical excitability; recovery curve analysis;

D O I：

10.1212/WNL.53.6.1347

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Seven untreated patients with idiopathic generalized epilepsy were studied with recovery curve analysis using transcranial magnetic stimulation and compared with 16 controls. Patients had a shorter period of inhibition of the test response following a conditioning stimulus and demonstrated a period of increased facilitation of the test response at interstimulus intervals of 200 to 300 msec, which was similar to the mean interdischarge interval of spike-wave activity on EEG. This provides further evidence of cortical hyperexcitability in idiopathic generalized epilepsy.

引用

页码：1347 / 1349

页数：3

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