Implant infection and infection resistant materials: A mini review

被引:76
作者
Arciola, CR
Alvi, FI
An, YH
Campoccia, D
Montanaro, L
机构
[1] Ist Ortoped Rizzoli, Res Unit Implant Infect, I-40136 Bologna, Italy
[2] Univ Bologna, Dept Expt Pathol, Bologna, Italy
[3] Med Univ S Carolina, Orthoped Res Lab, Charleston, SC 29425 USA
关键词
prosthetic infections; biofilm; MSCRAMM; biomaterials;
D O I
10.1177/039139880502801109
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Implant infection is an aggressive, often irreducible post-surgical infection. It remains the primary cause of implant failure. Bacterial contamination during surgery and subsequent adhesion onto biomaterial surface of opportunistic microorganisms, such as staphylococcal species, exopolysaccharidic slimes or specific adhesins, initiates the implant infection. Pathogenesis of periprosthestic infection is the focus of studies aimed at developing infection resistant materials.
引用
收藏
页码:1119 / 1125
页数:7
相关论文
共 62 条
[51]   INFECTION-RATES AFTER 3175 TOTAL HIP AND TOTAL KNEE REPLACEMENTS PERFORMED WITH AND WITHOUT A HORIZONTAL UNIDIRECTIONAL FILTERED AIR-FLOW SYSTEM [J].
SALVATI, EA ;
ROBINSON, RP ;
ZENO, SM ;
KOSLIN, BL ;
BRAUSE, BD ;
WILSON, PD .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1982, 64 (04) :525-535
[52]   Novel Strategies to Prevent Catheter-Associated Infections in Oncology Patients [J].
Schierholz, J. M. ;
Beuth, J. ;
Rump, A. ;
Koenig, D. -P. ;
Pulverer, G. .
JOURNAL OF CHEMOTHERAPY, 2001, 13 :239-250
[53]   Implant infections: a haven for opportunistic bacteria [J].
Schierholz, JM ;
Beuth, J .
JOURNAL OF HOSPITAL INFECTION, 2001, 49 (02) :87-93
[54]   Surveillance as a starting point to reduce surgical-site infection rates in elective orthopaedic surgery [J].
Schneeberger, PM ;
Smits, MHW ;
Zick, REF ;
Wille, JC .
JOURNAL OF HOSPITAL INFECTION, 2002, 51 (03) :179-184
[55]  
Sculco T P, 1993, Instr Course Lect, V42, P349
[56]   Potential applications of microbial surfactants in biomedical sciences [J].
Singh, P ;
Cameotra, SS .
TRENDS IN BIOTECHNOLOGY, 2004, 22 (03) :142-146
[57]   Biofilms and planktonic cells of Pseudomonas aeruginosa have similar resistance to killing by antimicrobials [J].
Spoering, AL ;
Lewis, K .
JOURNAL OF BACTERIOLOGY, 2001, 183 (23) :6746-6751
[58]   Designing surfaces that kill bacteria on contact [J].
Tiller, JC ;
Liao, CJ ;
Lewis, K ;
Klibanov, AM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (11) :5981-5985
[59]  
Trampuz A, 2005, SWISS MED WKLY, V135, P243
[60]   Infections associated with medical devices - Pathogenesis, management and prophylaxis [J].
von Eiff, C ;
Jansen, B ;
Kohnen, W ;
Becker, K .
DRUGS, 2005, 65 (02) :179-214