Potential applications of microbial surfactants in biomedical sciences

被引:434
作者
Singh, P [1 ]
Cameotra, SS [1 ]
机构
[1] Inst Microbial Technol, Chandigarh 160036, India
关键词
D O I
10.1016/j.tibtech.2004.01.010
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The main commercial use of biosurfactants is in pollution remediation because of their ability to stabilize emulsions. This enhances the solubility and availability of hydrophobic pollutants, thus increasing their potential for biodegradation. One useful property of many biosurfactants that has not been reviewed extensively is their antimicrobial activity. Several biosurfactants; have strong antibacterial, antifungal and antiviral activity. Other medically relevant uses of biosurfactants include their role as anti-adhesive agents to pathogens, making them useful for treating many diseases and as therapeutic and probiotic agents. Here, we discuss some of the new and exciting applications and related developments of various microbial surfactants in the field of biomedical sciences.
引用
收藏
页码:142 / 146
页数:5
相关论文
共 39 条
[1]   Biodegradation of soil-applied endosulfan in the presence of a biosurfactant [J].
Awasthi, N ;
Kumar, A ;
Makkar, R ;
Cameotra, SS .
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES, 1999, 34 (05) :793-803
[2]   Potential commercial applications of microbial surfactants [J].
Banat, IM ;
Makkar, RS ;
Cameotra, SS .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2000, 53 (05) :495-508
[3]   Immunonutrition: Role of biosurfactants, fiber, and probiotic bacteria [J].
Bengmark, S .
NUTRITION, 1998, 14 (7-8) :585-594
[4]  
BESSON F, 1976, J ANTIBIOT, V29, P1043, DOI 10.7164/antibiotics.29.1043
[5]   Role played by lactobacilli in controlling the population of vaginal pathogens [J].
Boris, S ;
Barbés, C .
MICROBES AND INFECTION, 2000, 2 (05) :543-546
[6]   Biosurfactant-enhanced bioremediation of polycyclic aromatic hydrocarbons [J].
Cameotra, SS ;
Bollag, JM .
CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY, 2003, 33 (02) :111-126
[7]   Synthesis of biosurfactants in extreme conditions [J].
Cameotra, SS ;
Makkar, RS .
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1998, 50 (05) :520-529
[8]   Paenibacillus koreensis sp nov., a new species that produces an iturin-like antifungal compound [J].
Chung, YR ;
Kim, CH ;
Hwang, I ;
Chun, J .
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 2000, 50 :1495-1500
[9]   BACILLOMYCIN L(C), A NEW ANTIBIOTIC OF THE ITURIN GROUP - ISOLATIONS, STRUCTURES, AND ANTIFUNGAL ACTIVITIES OF THE CONGENERS [J].
ESHITA, SM ;
ROBERTO, NH ;
BEALE, JM ;
MAMIYA, BM ;
WORKMAN, RF .
JOURNAL OF ANTIBIOTICS, 1995, 48 (11) :1240-1247
[10]   Massetolides A-H, antimycobacterial cyclic depsipeptides produced by two pseudomonads isolated from marine habitats [J].
Gerard, J ;
Lloyd, R ;
Barsby, T ;
Haden, P ;
Kelly, MT ;
Andersen, RJ .
JOURNAL OF NATURAL PRODUCTS, 1997, 60 (03) :223-229