Myelin under construction - teamwork required

被引：18

作者：

Boiko, T ^{[1
]}

Winckler, B ^{[1
]}

机构：

[1] Univ Virginia, Dept Neurosci, Charlottesville, VA 22908 USA

来源：

JOURNAL OF CELL BIOLOGY | 2006年 / 172卷 / 06期

关键词：

D O I：

10.1083/jcb.200602101

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Myelinating glial cells synthesize specialized myelin proteins and deposit them in the growing myelin sheath that enwraps axons multiple times. How do axons and myelinating glial cells coordinate this spectacular cell-cell interaction? In this issue, Trajkovic et al. (p. 937) show that neuronal signaling regulates cell surface expression of the myelin proteolipid protein in cultured oligodendrocytes in unexpected ways that may also contribute to myelination in situ.

引用

页码：799 / 801

页数：3

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