Palladium-catalyzed regio- and stereoselective synthesis of N-protected 2,4-dialkylated azacyclobutanes from amino allenes

被引：40

作者：

Anzai, M ^{[1
]}

Toda, A ^{[1
]}

Ohno, H ^{[1
]}

Takemoto, Y ^{[1
]}

Fujii, N ^{[1
]}

Ibuka, T ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Pharmaceut Sci, Sakyo Ku, Kyoto 6068501, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(99)01517-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed reaction of N-arylsulfonyl-1-alkyl-3,4-dienylamines with an aryl iodide in the presence of potassium carbonate in DMF at around 70 degrees C affords most predominantly the 2,4-cis-disubstituted azacyclobutanes bearing an aryl group on the double bond in good yields. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：7393 / 7397

页数：5

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