Scope of the Suzuki-Miyaura Cross-Coupling Reactions of Potassium Heteroaryltrifluoroborates

被引：201

作者：

Molander, Gary A. ^{[1
]}

Canturk, Belgin ^{[1
]}

Kennedy, Lauren E. ^{[1
]}

机构：

[1] Univ Penn, Dept Chem, Roy & Diana Vagelos Labs, Philadelphia, PA 19104 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 74卷 / 03期

基金：

美国国家卫生研究院;

关键词：

ARYLBORONIC ACIDS; BORONIC ACIDS; HALOPYRIDINYLBORONIC ACIDS; HETEROARYL BROMIDES; CYCLOADDITION ROUTE; EFFICIENT; ARYL; DERIVATIVES; CHLORIDES; CATALYSTS;

D O I：

10.1021/jo802590b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A wide variety of bench-stable potassium heteroaryltrifluoroborates were prepared, and general reaction conditions were developed for their cross-coupling to aryl and heteroaryl halides. The cross-coupled products were obtained in good to excellent yields. This method represents an efficient and facile installation of heterocyclic building blocks onto preexisting organic substructures.

引用

页码：973 / 980

页数：8

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