Regioselectivity in the palladium-catalyzed addition of carbon nucleophiles to dihydropyran derivatives

被引：18

作者：

Brescia, MR ^{[1
]}

Shimshock, YC ^{[1
]}

DeShong, P ^{[1
]}

机构：

[1] UNIV MARYLAND,DEPT CHEM & BIOCHEM,COLLEGE PK,MD 20742

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1997年 / 62卷 / 05期

关键词：

D O I：

10.1021/jo961973d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The regioselectivity of Pd-catalyzed malonate or sulfonylacetate addition to dihydropyran derivatives is highly dependent upon the substitution pattern of the dihydropyran nucleus and is governed by electronic, rather than steric factors. In certain instances, subtle steric features also play a role in controlling regioselectivity by altering the conformation of the intermediate eta(3)-allyl Pd-complex.

引用

页码：1257 / 1263

页数：7

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