A highly regio- and chemoselective reductive cleavage of benzylidene acetals with EtAlCl2-Et3SiH

被引：24

作者：

Balakumar, V ^{[1
]}

Aravind, A ^{[1
]}

Baskaran, S ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Madras 600036, Tamil Nadu, India

来源：

SYNLETT | 2004年 / 04期

关键词：

regioselectivity; chemoselectivity; reductive cleavage; benzylidene acetal; EtAlCl2; Et3SiH;

D O I：

10.1055/s-2004-817752

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly regio- and chemoselective reductive cleavage of benzylidene acetals derived from 1,2- and 1,3-diols was achieved under mild conditions using EtAlCl2-Et3SiH reagent system in good to excellent yields. Labile protecting groups such as N-Boc, N-Cbz and -OTBDMS are found to be stable under the reaction conditions.

引用

页码：647 / 650

页数：4

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