Do we need additional markers of myocyte necrosis: the potential value of heart fatty-acid-binding protein

被引：122

作者：

Alhadi, HA ^{[1
]}

Fox, KAA ^{[1
]}

机构：

[1] Univ Edinburgh, Royal Infirm Edinburgh, Ctr Cardiovasc Sci, Cardiovasc Res Unit, Edinburgh, Midlothian, Scotland

来源：

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE | 2004年 / 97卷 / 04期

关键词：

D O I：

10.1093/qjmed/hch037

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart fatty-acid-binding protein (FABP) is a small cytosolic protein that is abundant in the heart and has low concentrations in the blood and in tissues outside the heart. It appears in the blood as early as 1.5 h after onset of symptoms of infarction, peaks around 6 h and returns to baseline values in 24 h. These features of H-FABP make it an excellent potential candidate for the detection of acute myocardial infarction (AMI). We review the strengths and weaknesses of H-FABP as a clinically applicable marker of myocyte necrosis in the context of acute coronary syndromes.

引用

页码：187 / 198

页数：12

共 126 条

[121] FATTY-ACID-BINDING PROTEINURIA DIAGNOSES MYOCARDIAL-INFARCTION IN THE RAT [J].