The mar regulon:: multiple resistance to antibiotics and other toxic chemicals

被引:298
作者
Alekshun, MN [1 ]
Levy, SB
机构
[1] Tufts Univ, Sch Med, Dept Mol Biol & Microbiol, Ctr Adaptat Genet & Drug Resistance, Boston, MA 02111 USA
[2] Tufts Univ, Sch Med, Dept Med, Boston, MA 02111 USA
关键词
D O I
10.1016/S0966-842X(99)01589-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The chromosomal multiple antibiotic resistance (mar) locus of Escherichia coli and other members of the Enterobacteriaceae controls resistance to multiple, structurally unrelated compounds including antibiotics, household disinfectants, organic solvents and other toxic chemicals. The Mar phenotype is induced following exposure to a variety of chemicals with aromatic rings.
引用
收藏
页码:410 / 413
页数:4
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